Immunology and rheumatology: clinical-trial pipeline
31,579 immunology and rheumatology trials are in ClinicalTrials.gov and the EU CTIS portal; 7,041 are not yet finished and 726 of those are in phase 2/3 or 3. Source: Arcadium Data, data as of .
Open trials by phase
| Phase | Trials |
|---|---|
| Not applicable | 4,094 |
| Phase 2 | 900 |
| Phase 3 | 606 |
| Phase 4 | 455 |
| Phase 1 | 453 |
| Phase 1/2 | 253 |
| Early phase 1 | 158 |
| Phase 2/3 | 120 |
| Not stated | 2 |
Sponsors with the most open trials
Recently changed open trials
| Registry id | Title | Sponsor | Phase | Status | Countries |
|---|---|---|---|---|---|
| NCT06333483 | Obe-cel in Adolescent [Applicable in UK Only] and Adult Severe, Refractory Systemic Lupus Erythematosus | Autolus Limited | Phase 1 | Active, not recruiting | Spain, United Kingdom |
| NCT06220604 | A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis (ICONIC-AD… | Janssen Research & Development, LLC | Phase 3 | Active, not recruiting | Australia, Brazil, Canada, Germany +8 |
| NCT06133192 | Steroids Versus ECP and Steroids as First-line Treatment of Grade II Acute GVHD | Central Hospital, Nancy, France | Phase 2 | Recruiting | France |
| NCT06100744 | A Study to Assess Adverse Events, Change in Disease Activity, and How the Drug Moves Through the Body in Chil… | AbbVie | Phase 3 | Not yet recruiting | Australia, Canada, Germany, Spain +5 |
| NCT06012240 | A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants… | AbbVie | Phase 3 | Recruiting | Argentina, Australia, Belgium, Bulgaria +23 |
| NCT05531565 | A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants W… | Biogen | Phase 2/3 | Active, not recruiting | Argentina, Belgium, Bulgaria, Brazil +26 |
| NCT05169229 | Antibiotic Impregnated Bone Graft to Reduce Infection in Hip Replacement. | University Hospital, Linkoeping | Phase 2 | Not yet recruiting | Denmark, Sweden |
| NCT05076175 | A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcera… | Bristol-Myers Squibb | Phase 2/3 | Recruiting | Australia, Belgium, Canada, Germany +9 |
| NCT04963296 | A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With Systemic Lupus Erythematosus | Hoffmann-La Roche | Phase 3 | Active, not recruiting | Argentina, Brazil, Czechia, Spain +10 |
| 2024-512269-14-00 | MEthotrexate versus TOcilizumab for treatment of GIant cell Arteritis: a multicenter, randomized, controlled… | Centre Hospitalier Universitaire De Dijon | Phase 3 | Active, not recruiting | France |
| 2023-506656-24-00 | Immediate corticosteroid therapy and rituximab to prevent generalization in ocular myasthenia gravis: a PROBE… | Hopital Fondation Adolphe De Rothschild | Phase 3 | Recruiting | France |
| NCT06118411 | A Study To Assess Adverse Events and Effectiveness of Upadacitinib Oral Tablets in Adult and Adolescent Parti… | AbbVie | Phase 3 | Active, not recruiting | Argentina, Belgium, Bulgaria, Canada +15 |
| NCT06072183 | A 104-Week Study of Ritlecitinib Oral Capsules in Adults With Nonsegmental Vitiligo (Active and Stable) Tranq… | Pfizer | Phase 3 | Active, not recruiting | Australia, Belgium, Bulgaria, Canada +13 |
| NCT06046222 | Trial of Efficacy and Safety of NS-229 Versus Placebo in Patients With Eosinophilic Granulomatosis With Polya… | NS Pharma, Inc. | Phase 2 | Not yet recruiting | Canada, Germany, Spain, France +4 |
| NCT04540497 | A Study of Inebilizumab Efficacy and Safety in IgG4- Related Disease | Amgen | Phase 3 | Active, not recruiting | Argentina, Australia, Canada, China +16 |
| 2023-509114-11-00 | Intra-articular corticosteroid injection vs arthrocentesis in the management of clinical arthritis of the tem… | Vaestra Goetalandsregionen | Phase 4 | Recruiting | Sweden |
| 2023-508634-34-00 | Interventional, multicenter, open-label, randomized, non-comparative trial evaluating the safety, in terms of… | Inserm | Phase 2 | Recruiting | France |
| NCT04895241 | A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms o… | Biogen | Phase 3 | Active, not recruiting | Australia, Bulgaria, Brazil, Chile +11 |
| NCT04629833 | Treatment Of Steroid-Refractory Acute Graft-versus-host Disease With Mesenchymal Stromal Cells Versus Best Av… | medac GmbH | Phase 3 | Recruiting | Germany, Spain, France, Poland +1 |
| NCT04157348 | Efficacy and Safety of Benralizumab in EGPA Compared to Mepolizumab. | AstraZeneca | Phase 3 | Active, not recruiting | Belgium, Canada, Germany, France +5 |
All areas: clinical-trial pipeline by sponsor.
Track a sponsor's pipeline
The API returns the same trials by sponsor website, phase, status, condition and country with a change feed, joined to hiring and public contract awards. Try it without a key on one sponsor.
Sources: ClinicalTrials.gov (U.S. National Library of Medicine, public domain) and the EU Clinical Trials Information System public portal (European Medicines Agency), data as of 2026-10-25. A trial that one register cites in the other is shown once. Organisation-level data only: investigators, contact persons and site names are not stored, and a sponsor that could be a private person is withheld. Sponsor-to-website matches are made by name and can be wrong; check the register before relying on a record. Independent of the NLM, NIH and EMA.
Cite as: Arcadium Data, "Immunology and rheumatology clinical trials: 7,041 open, 726 in phase 3", https://arcadiumdata.io/clinical-trials/area/immunology-rheumatology/, data as of 2026-10-25.