Mayo Clinic: clinical-trial pipeline
Mayo Clinic is the sponsor of 3,258 clinical trials in ClinicalTrials.gov and the EU CTIS portal; 820 are not yet finished and 26 were first posted in the last 90 days. Source: Arcadium Data, data as of .
Open trials820
Phase 2/3 and 3141
Countries43
New in 90 days26
Trials by phase
| Phase | Trials |
|---|---|
| Not applicable | 2,062 |
| Phase 2 | 379 |
| Phase 1 | 282 |
| Phase 4 | 193 |
| Phase 1/2 | 104 |
| Early phase 1 | 97 |
| Phase 3 | 93 |
| Phase 2/3 | 48 |
Trials by status
| Status | Trials |
|---|---|
| Completed | 1,936 |
| Recruiting | 617 |
| Terminated | 304 |
| Withdrawn or not authorised | 181 |
| Active, not recruiting | 150 |
| Not yet recruiting | 53 |
| Suspended or halted | 17 |
Condition areas
| Area | Trials |
|---|---|
| Oncology | 934 |
| Cardiovascular | 421 |
| Gastroenterology and liver | 310 |
| Nephrology and urology | 254 |
| Metabolic and endocrine (diabetes, obesity) | 251 |
| Neurology | 190 |
| Immunology and rheumatology | 174 |
| Rare and genetic diseases | 166 |
| Infectious disease and vaccines | 154 |
| Musculoskeletal | 148 |
| Respiratory | 119 |
| Psychiatry and mental health | 101 |
Countries
| Country | Trials |
|---|---|
| United States | 3,111 |
| Canada | 23 |
| Spain | 4 |
| Israel | 4 |
| Australia | 3 |
| China | 3 |
| United Kingdom | 3 |
| India | 3 |
| Italy | 3 |
| Brazil | 2 |
| Germany | 2 |
| France | 2 |
| Croatia | 2 |
| Hungary | 2 |
| Iceland | 2 |
Latest changes
| Day | Change | Trial |
|---|---|---|
| 2026-10-22 | New trial posted | A Community Based Intervention to Improve Cervical Cancer Screening Among Women in the Hi… |
| 2026-10-21 | New trial posted | Evaluation of a Point-of-Care, AI-Powered Spectroscopy Device for Triage of Suspicious Vu… |
| 2026-10-19 | New trial posted | Conducting Wound, Ostomy, and Continence (WOC) Nurse Telephone Follow-up for Post-dischar… |
| 2026-10-16 | New trial posted | Evaluating the Efficacy of a "Quiet Knee Protocol" in Primary Total Knee Arthroplasty (TK… |
| 2026-10-15 | New trial posted | Varenicline for Smoking Cessation in Pancreatitis |
| 2026-10-09 | New trial posted | Intraoperative Microelectrode Recordings Using MAVEN Compared to Standard Recording Appar… |
| 2026-10-07 | New trial posted | EEG-Guided Transcranial Magnetic Stimulation for Adults With Depression |
| 2026-10-02 | New trial posted | Adding Spatially Fractionated Radiation Therapy to Standard Palliative Radiation for Impr… |
| 2026-09-30 | New trial posted | SMS-Based Remote Symptom Monitoring for Patients With Plasma Cell Disorders |
| 2026-09-28 | New trial posted | Nemolizumab for the Treatment of Moderate to Severe Chronic Hepatic Pruritus |
| 2026-09-24 | New trial posted | Lower Body Negative Pressure to Validate Physiological Monitors |
| 2026-09-24 | New trial posted | A Pilot Investigation of Pain Reprocessing Therapy for Functional Dyspepsia |
Open trials
The 25 most recently changed open trials.
| Registry id | Title | Phase | Status | Countries |
|---|---|---|---|---|
| NCT06057909 | A Study of Neurodegeneration and Neuronal Fluctuations in Lewy Body Disease and Alzheimer's Disease | Not applicable | Recruiting | United States |
| NCT04992650 | Ultrasonic Perfusion Imaging in Post-mastectomy Irradiated Patients | Not applicable | Recruiting | United States |
| NCT06483048 | MUC1-Activated T Cells for the Treatment of Relapsed and Resistant Ovarian Cancer | Phase 1 | Recruiting | United States |
| NCT06306963 | Prevalence of Gastric Motor Dysfunction and Upper GI Symptoms in Gastric Antral Vascular Ectasias | Not applicable | Recruiting | United States |
| NCT05773300 | Registry for Mayo Clinic Adult Congenital Heart Disease Control Population | Not applicable | Active, not recruiting | United States |
| NCT07662824 | Flyte Device for Improving Urinary Incontinence Among Endometrial and Cervical Cancer Survivors Who Have Unde… | Not applicable | Recruiting | United States |
| NCT04532814 | Exercise-stimulated Muscle Glucose Uptake in Upper Body Obesity | Not applicable | Active, not recruiting | United States |
| NCT06940271 | Feasibility and Effect of Wrapping Nerves With a Multi-Layer Perinatal Tissue Allograft During Prostatectomy | Not applicable | Recruiting | United States |
| NCT05793567 | A Study of Microcirculatory Function in Type 2 Myocardial Infarction (T2MI) | Not applicable | Not yet recruiting | United States |
| NCT04197934 | WSD0922-FU for Treatment of Glioblastoma, Anaplastic Astrocytoma, or Non-small Cell Lung Cancer With Central… | Phase 1 | Active, not recruiting | United States |
| NCT02740634 | Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal Study | Not applicable | Recruiting | United States |
| NCT07455370 | A Study of Moral Distress, Moral Injury and Post-Traumatic Stress for Nurses | Not applicable | Recruiting | United States |
| NCT05477277 | Adverse Outcomes and Mortality in Liver Transplant | Not applicable | Recruiting | United States |
| NCT07755176 | Patient-reported Outcomes Following Percutaneous Ablation of Desmoid Tumors | Not applicable | Recruiting | United States |
| NCT07879014 | Evaluating the Efficacy of a "Quiet Knee Protocol" in Primary Total Knee Arthroplasty (TKA): A Prospective Ra… | Not applicable | Recruiting | United States |
| NCT06999798 | An Optimized Ultrasound Twinkling Marker for the Imaging of Lymph Nodes in Patients With Clinically Node-Posi… | Phase 1 | Recruiting | United States |
| NCT06640010 | Using Induced-Pluripotent Stem Cells to Model Cancer Therapy-Related Adverse Events | Not applicable | Recruiting | United States |
| NCT03478761 | 24-Hydroxylase Deficiency and CYP24A1 Mutation Patient Registry | Not applicable | Recruiting | United States |
| NCT04858009 | Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Pancreatic Cancer and Peritoneal Metastasis | Phase 2 | Active, not recruiting | United States |
| NCT03842007 | Understanding Mechanisms of Normal and Disordered Defecation | Not applicable | Recruiting | United States |
| NCT07210437 | Longitudinal Autonomic Characterization as a Predictor for Secondary Medical Complications Post-SCI | Not applicable | Recruiting | United States |
| NCT03833622 | Shared Decision Making to Improve Goals of Care in the ED | Not applicable | Recruiting | United States |
| NCT05222620 | SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial | Phase 2 | Recruiting | United States |
| NCT04630613 | NOX4 and Related Biomarkers in ADPKD | Not applicable | Recruiting | United States |
| NCT06236711 | Transcranial Direct Current Stimulation (tDCS) as an Adjunctive Treatment for Treatment Resistant Depression… | Not applicable | Active, not recruiting | United States |
All sponsors: clinical-trial pipeline by sponsor.
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Sources: ClinicalTrials.gov (U.S. National Library of Medicine, public domain) and the EU Clinical Trials Information System public portal (European Medicines Agency), data as of 2026-10-25. A trial that one register cites in the other is shown once. Organisation-level data only: investigators, contact persons and site names are not stored, and a sponsor that could be a private person is withheld. Sponsor-to-website matches are made by name and can be wrong; check the register before relying on a record. Independent of the NLM, NIH and EMA.
Cite as: Arcadium Data, "Mayo Clinic clinical trials: 820 open, 141 in phase 3", https://arcadiumdata.io/clinical-trials/sponsor/mayo-clinic/, data as of 2026-10-25.