Massachusetts General Hospital: clinical-trial pipeline
Massachusetts General Hospital is the sponsor of 2,582 clinical trials in ClinicalTrials.gov and the EU CTIS portal; 591 are not yet finished and 21 were first posted in the last 90 days. Source: Arcadium Data, data as of .
Open trials591
Phase 2/3 and 398
Countries40
New in 90 days21
Trials by phase
| Phase | Trials |
|---|---|
| Not applicable | 1,662 |
| Phase 2 | 323 |
| Phase 4 | 229 |
| Phase 1 | 142 |
| Phase 3 | 74 |
| Phase 1/2 | 71 |
| Early phase 1 | 57 |
| Phase 2/3 | 24 |
Trials by status
| Status | Trials |
|---|---|
| Completed | 1,447 |
| Recruiting | 352 |
| Terminated | 216 |
| Withdrawn or not authorised | 161 |
| Unknown | 159 |
| Active, not recruiting | 151 |
| Not yet recruiting | 88 |
| Suspended or halted | 8 |
Condition areas
| Area | Trials |
|---|---|
| Oncology | 564 |
| Psychiatry and mental health | 465 |
| Cardiovascular | 233 |
| Rare and genetic diseases | 219 |
| Metabolic and endocrine (diabetes, obesity) | 214 |
| Infectious disease and vaccines | 187 |
| Gastroenterology and liver | 162 |
| Neurology | 134 |
| Musculoskeletal | 123 |
| Immunology and rheumatology | 104 |
| Nephrology and urology | 99 |
| Respiratory | 97 |
Countries
| Country | Trials |
|---|---|
| United States | 2,362 |
| Uganda | 31 |
| South Africa | 22 |
| Canada | 13 |
| Australia | 9 |
| Italy | 8 |
| Germany | 6 |
| Kenya | 6 |
| India | 4 |
| Puerto Rico | 4 |
| Spain | 3 |
| Nepal | 3 |
| Bangladesh | 2 |
| China | 2 |
| United Kingdom | 2 |
Latest changes
| Day | Change | Trial |
|---|---|---|
| 2026-10-23 | New trial posted | Effect of Neurofeedback and TMS |
| 2026-10-23 | New trial posted | Pilot Study of a Behavioral Program for Depression in Skilled Nursing Facility Residents… |
| 2026-10-23 | New trial posted | Reducing Arterial Inflammation Using Eplerenone and Statins in HIV |
| 2026-10-21 | New trial posted | Symptom Monitoring and Management Intervention After CAR-T |
| 2026-10-19 | New trial posted | Semaglutide for the Treatment of Cannabis Use Disorder |
| 2026-10-15 | New trial posted | A Study to Test New Investigational Drugs (LCFA-01and LC103) for Bacterial Vaginosis (BV)… |
| 2026-10-14 | New trial posted | Non-Contrast-Enhanced Breast MRI in the Evaluation of Newly Diagnosed Breast Cancer: A Pi… |
| 2026-10-09 | New trial posted | Leveraging Interventions for Caregiver Growth, Health, Training, Empowerment and Navigati… |
| 2026-10-08 | New trial posted | Blood Volume Monitoring Via Critline in Volume Overload: Hospitalization and Readmission |
| 2026-10-06 | New trial posted | Augmenting Clinical Workflow With a Structured Chatbot for Patient History Collection and… |
| 2026-09-24 | New trial posted | Delayed-Release, Extended-Release Methylphenidate (Jornay PM) for Adolescents and Young A… |
| 2026-09-14 | New trial posted | Molecular Imaging to Identify Predictors of Aortic Valve Disease Activity |
Open trials
The 25 most recently changed open trials.
| Registry id | Title | Phase | Status | Countries |
|---|---|---|---|---|
| NCT05237258 | Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia | Not applicable | Recruiting | United States |
| NCT02792270 | Caloric Restriction In Sarcoma Patients Treated With Pre-Operative RT | Not applicable | Recruiting | United States |
| NCT05900401 | Delayed Tolerance Through Mixed Chimerism | Phase 1/2 | Recruiting | United States |
| NCT07892287 | Effect of Neurofeedback and TMS | Not applicable | Not yet recruiting | |
| NCT06707493 | Ivosidenib as Post-HSCT Maintenance for AML | Phase 2 | Recruiting | United States |
| NCT06487351 | Intervention to Reduce Implicit Bias in Pharmacies | Not applicable | Not yet recruiting | United States |
| NCT06003153 | GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH | Phase 4 | Recruiting | United States |
| NCT07514416 | To Test a New Drug (LCFA-01) for Safety and PK in Healthy Adults for Bacterial Vaginosis Infection. | Phase 1 | Active, not recruiting | Australia |
| NCT05671133 | Effectiveness and Implementation of a Clinician Decision Support System to Prevent Suicidal Behaviors | Not applicable | Recruiting | United States |
| NCT07765836 | Vilastobart+Retifanlimab in BRCA or PALB2 Deficient PC | Phase 2 | Not yet recruiting | United States |
| NCT06075693 | Cerebrospinal Fluid Biomarkers of Myotonic Dystrophy | Not applicable | Recruiting | United States |
| NCT05019625 | Biomarker Development for Muscular Dystrophies | Not applicable | Recruiting | United States |
| NCT05418959 | Genetic Risk Stratification of Pediatric Skin Lesions | Phase 1 | Recruiting | United States |
| NCT07610928 | Stress Management and Meditative Movements for Asian Americans With Depression and Physical Symptoms | Not applicable | Recruiting | United States |
| NCT03270072 | The Differential Impact of Proton Beam Irradiation Versus Conventional Radiation on Organs-at-risk in Stage I… | Not applicable | Active, not recruiting | United States |
| NCT07166861 | Annual Wellness Visits vs GRACE-augmented Annual Wellness Visits For Older Adults With High Needs - Phase 2 | Not applicable | Recruiting | United States |
| NCT01521741 | Prospective Screening for Breast Cancer-related Lymphedema | Not applicable | Recruiting | United States |
| NCT05056896 | ASPIRED-XT: ASPirin Intervention for the REDuction of Colorectal Cancer Risk -EXTension | Early phase 1 | Active, not recruiting | United States |
| NCT06406114 | Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing | Phase 2 | Recruiting | United States |
| NCT07102797 | ActiveGirls: Physical Activity, Hormone Health, and Diabetes Risk in Early Adolescence | Not applicable | Recruiting | United States |
| NCT07785648 | Mindfulness-Based Cognitive Therapy Vs. the Health Enhancement Program for Chronic Pain and Early Cognitive D… | Not applicable | Not yet recruiting | United States |
| NCT07723066 | Biomarker Discovery for Suicide Precision Circuit Therapeutics | Not applicable | Not yet recruiting | |
| NCT07358195 | Addition of Venetoclax to Combined Hematopoietic Stem Cell and Kidney Transplantation | Early phase 1 | Recruiting | United States |
| NCT06283953 | Boosting Resources for Tracheostomy Care at Home | Not applicable | Recruiting | United States |
| NCT07793071 | Oral Thiamine (Vitamin B1) for Depression in Children and Adolescents | Phase 2 | Not yet recruiting |
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Sources: ClinicalTrials.gov (U.S. National Library of Medicine, public domain) and the EU Clinical Trials Information System public portal (European Medicines Agency), data as of 2026-10-25. A trial that one register cites in the other is shown once. Organisation-level data only: investigators, contact persons and site names are not stored, and a sponsor that could be a private person is withheld. Sponsor-to-website matches are made by name and can be wrong; check the register before relying on a record. Independent of the NLM, NIH and EMA.
Cite as: Arcadium Data, "Massachusetts General Hospital clinical trials: 591 open, 98 in phase 3", https://arcadiumdata.io/clinical-trials/sponsor/massachusetts-general-hospital/, data as of 2026-10-25.