National Institute of Allergy and Infectious Diseases (NIAID): clinical-trial pipeline
National Institute of Allergy and Infectious Diseases (NIAID) is the sponsor of 2,443 clinical trials in ClinicalTrials.gov and the EU CTIS portal; 215 are not yet finished and 6 were first posted in the last 90 days. Source: Arcadium Data, data as of .
Trials by phase
| Phase | Trials |
|---|---|
| Phase 1 | 810 |
| Not applicable | 712 |
| Phase 2 | 521 |
| Phase 3 | 158 |
| Phase 1/2 | 151 |
| Phase 4 | 61 |
| Early phase 1 | 17 |
| Phase 2/3 | 13 |
Trials by status
| Status | Trials |
|---|---|
| Completed | 1,924 |
| Terminated | 183 |
| Recruiting | 170 |
| Withdrawn or not authorised | 96 |
| Active, not recruiting | 33 |
| Unknown | 21 |
| Not yet recruiting | 12 |
| Suspended or halted | 4 |
Condition areas
| Area | Trials |
|---|---|
| Infectious disease and vaccines | 1,859 |
| Rare and genetic diseases | 430 |
| Immunology and rheumatology | 271 |
| Respiratory | 151 |
| Gastroenterology and liver | 127 |
| Nephrology and urology | 68 |
| Dermatology | 65 |
| Metabolic and endocrine (diabetes, obesity) | 52 |
| Oncology | 44 |
| Women's health and obstetrics | 39 |
| Cardiovascular | 34 |
| Neurology | 33 |
Countries
| Country | Trials |
|---|---|
| United States | 2,090 |
| Puerto Rico | 184 |
| South Africa | 93 |
| Thailand | 66 |
| Uganda | 64 |
| Brazil | 63 |
| Mali | 63 |
| Canada | 50 |
| Zimbabwe | 41 |
| Peru | 39 |
| Tanzania | 37 |
| Kenya | 34 |
| Malawi | 30 |
| India | 29 |
| Botswana | 28 |
Latest changes
| Day | Change | Trial |
|---|---|---|
| 2026-10-20 | New trial posted | A Clinical Study to Assess the Efficacy of Weekly Doxycycline Prophylaxis to Reduce Bacte… |
| 2026-10-19 | New trial posted | A Clinical Study of Ixazomib to Reactivate HIV and Reduce HIV Reservoir Size |
| 2026-10-09 | New trial posted | Firefighter's Longitudinal Airway and Respiratory Exposome/Multiome Study (FLARES) |
| 2026-10-06 | New trial posted | Positron Emission Tomography and Organ-Specific Changes in Participants Co-Enrolled in NI… |
| 2026-09-14 | New trial posted | A Clinical Study of the HCMV-TB Vaccine Candidate VIR-1778 in Healthy Adults |
| 2026-09-03 | New trial posted | A Clinical Study to Evaluate the Safety and Immunogenicity of a Higher Dose of the Study… |
Open trials
The 25 most recently changed open trials.
| Registry id | Title | Phase | Status | Countries |
|---|---|---|---|---|
| NCT07611435 | Beginning to Assess an Appropriate CONtrol for Oral Food Challenges in Alpha-Gal Syndrome (CoFAR-13) - BeACON… | Phase 2 | Recruiting | United States |
| NCT00091871 | A Longitudinal Study of Familial Hypereosinophilia (FE): Natural History and Markers of Disease Progression | Not applicable | Recruiting | United States |
| NCT01168271 | Host and Parasite Factors That Influence Susceptibility to Malaria Infection and Disease During Pregnancy and… | Not applicable | Recruiting | Mali |
| NCT03878121 | Safety and Immunogenicity of Ad4-HIV Envelope Vaccine Vectors in Healthy Volunteers | Phase 1 | Recruiting | United States |
| NCT00001205 | Natural History of Treated Neurocysticercosis and Long-Term Outcomes | Not applicable | Recruiting | United States |
| NCT02190266 | Pathogenesis and Genetics of Disseminated or Refractory Coccidioidomycosis | Not applicable | Recruiting | United States |
| NCT03538600 | Sample Collection From Healthy Volunteers for Assay Optimization | Not applicable | Recruiting | United States |
| NCT06680843 | Characterization of Human Immune Signatures to Zoonotic Virus Exposure in Cambodia | Not applicable | Recruiting | Cambodia |
| NCT03937817 | Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants | Not applicable | Recruiting | United States |
| NCT00004317 | Pyrimethamine, Sulfadiazine, and Leucovorin in Treating Patients With Congenital Toxoplasmosis | Phase 4 | Recruiting | United States |
| NCT00001351 | Evaluation and Long-Term Follow-up of Patients With Inflammatory Disorders | Not applicable | Recruiting | United States |
| NCT00767312 | Analysis of HIV-1 Replication During Antiretroviral Therapy | Not applicable | Recruiting | United States |
| NCT00246857 | Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell Death | Not applicable | Recruiting | United States |
| NCT06908096 | Epstein-Barr Virus (EBV) gH/gL/gp42-Ferritin Nanoparticle Vaccine With or Without gp350-Ferritin in Healthy A… | Phase 1 | Recruiting | United States |
| NCT00039689 | Leukapheresis Procedures to Obtain Plasma and Lymphocytes for Research Studies on Antiretroviral Naive HIV-1… | Not applicable | Recruiting | United States |
| NCT06851767 | Base-Edited Hematopoietic Stem/Progenitor Cell X-Linked Severe Combined Immunodeficiency Gene Therapy | Phase 1/2 | Recruiting | United States |
| NCT06987318 | A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT… | Phase 1 | Not yet recruiting | Brazil, Peru, United States |
| NCT00018044 | Study of Mycobacterial Infections | Not applicable | Recruiting | United States |
| NCT07703475 | A Safety, Reactogenicity and Immunogenicity Trial of RVX-sCPD9 Booster Intranasal COVID-19 Vaccine | Phase 1 | Not yet recruiting | United States |
| NCT07027826 | The Esophageal String Test as a Diagnostic Screening Tool for Eosinophilic Esophagitis Among Africans With Dy… | Not applicable | Recruiting | Mali, United States |
| NCT06517693 | Safety and Pharmacokinetics Study of PGT121.414.LS Alone and in Combination With VRC07-523LS in Infants Expos… | Phase 1 | Recruiting | Brazil, Kenya, Puerto Rico, United States +2 |
| NCT00001316 | Viral Load in Blood and Lymph Tissues in People Living With HIV | Not applicable | Recruiting | United States |
| NCT07015996 | Efficacy of Tezepelumab in Peanut Oral Immunotherapy | Phase 2 | Recruiting | United States |
| NCT05017545 | Carfilzomib and Belatacept for Desensitization | Phase 1/2 | Active, not recruiting | United States |
| NCT07549503 | Early Signals of the Transition From Immune Quiescence to Activation in the Liver Allograft Microenvironment… | Phase 2 | Recruiting | United States |
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Sources: ClinicalTrials.gov (U.S. National Library of Medicine, public domain) and the EU Clinical Trials Information System public portal (European Medicines Agency), data as of 2026-10-25. A trial that one register cites in the other is shown once. Organisation-level data only: investigators, contact persons and site names are not stored, and a sponsor that could be a private person is withheld. Sponsor-to-website matches are made by name and can be wrong; check the register before relying on a record. Independent of the NLM, NIH and EMA.
Cite as: Arcadium Data, "National Institute of Allergy and Infectious Diseases (NIAID) clinical trials: 215 open, 171 in phase 3", https://arcadiumdata.io/clinical-trials/sponsor/national-institute-of-allergy-and-infectious-diseases-niaid/, data as of 2026-10-25.