University of North Carolina, Chapel Hill: clinical-trial pipeline
University of North Carolina, Chapel Hill is the sponsor of 1,366 clinical trials in ClinicalTrials.gov and the EU CTIS portal; 164 are not yet finished and 10 were first posted in the last 90 days. Source: Arcadium Data, data as of .
Trials by phase
| Phase | Trials |
|---|---|
| Not applicable | 1,046 |
| Phase 2 | 102 |
| Phase 1 | 91 |
| Phase 4 | 71 |
| Phase 1/2 | 19 |
| Early phase 1 | 17 |
| Phase 3 | 15 |
| Phase 2/3 | 5 |
Trials by status
| Status | Trials |
|---|---|
| Completed | 1,058 |
| Recruiting | 112 |
| Terminated | 86 |
| Withdrawn or not authorised | 51 |
| Active, not recruiting | 31 |
| Not yet recruiting | 21 |
| Suspended or halted | 7 |
Condition areas
| Area | Trials |
|---|---|
| Infectious disease and vaccines | 269 |
| Psychiatry and mental health | 150 |
| Metabolic and endocrine (diabetes, obesity) | 117 |
| Rare and genetic diseases | 111 |
| Respiratory | 101 |
| Cardiovascular | 99 |
| Immunology and rheumatology | 84 |
| Women's health and obstetrics | 78 |
| Gastroenterology and liver | 73 |
| Neurology | 52 |
| Nephrology and urology | 49 |
| Musculoskeletal | 47 |
Countries
| Country | Trials |
|---|---|
| United States | 1,169 |
| Malawi | 38 |
| Zambia | 31 |
| Puerto Rico | 24 |
| Canada | 16 |
| China | 9 |
| Uganda | 7 |
| South Africa | 7 |
| Vietnam | 6 |
| India | 4 |
| Australia | 3 |
| Ethiopia | 3 |
| Kenya | 3 |
| New Zealand | 3 |
| Tanzania | 3 |
Latest changes
| Day | Change | Trial |
|---|---|---|
| 2026-10-14 | New trial posted | Study to Evaluate the Effects of Oral Glyceryl Guiacolate (Guaifenesin, GGE) on Sputum Rh… |
| 2026-10-09 | New trial posted | Post-traumatic Estradiol Administration and Care Evaluation (PEACE) |
| 2026-09-18 | New trial posted | Pilot HIV Self-Testing And Self-collected STI Testing Strategy for Sex Worker Empowerment… |
| 2026-09-17 | New trial posted | Light Bulb Stimuli to Reduce Chronic Pain |
| 2026-09-02 | New trial posted | Evaluation of the Melanin-Adjusted Blood Oxygen Sensor (MABOS) in ICU Settings |
| 2026-09-02 | New trial posted | Single Session Personalized Aperiodic Transcranial Alternating Current Stimulation (PandA… |
| 2026-09-02 | New trial posted | Mediterranean Dietary Intervention for HS |
| 2026-08-31 | New trial posted | Creatine for Recovery and Thinking in Mothers |
| 2026-08-28 | New trial posted | Daily Upgrade Trial |
| 2026-08-26 | New trial posted | Efficacy of Potassium-Competitive Acid Blockers in Barrett's Esophagus (PCAB BE Study) |
Open trials
The 25 most recently changed open trials.
| Registry id | Title | Phase | Status | Countries |
|---|---|---|---|---|
| NCT06096324 | Education and Employment Support for HIV Prevention in Young Adults (ENSPIRE) | Not applicable | Recruiting | United States |
| NCT04262167 | Human Autologous Lung Stem Cell Transplant for Idiopathic Pulmonary Fibrosis | Phase 1 | Active, not recruiting | United States |
| NCT06636786 | Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TN… | Phase 2 | Recruiting | United States |
| NCT00804583 | Genetic Modifiers of Cystic Fibrosis (CF) Liver Disease | Not applicable | Active, not recruiting | United States |
| NCT07337902 | Comparing Over the Counter Pain Medicines for Discomfort in Crohn's Disease (AVID-CD) | Not applicable | Recruiting | United States |
| NCT05398250 | A Comparison of Two Brief Suicide Prevention Interventions Tailored for Youth on the Autism Spectrum | Not applicable | Recruiting | United States |
| NCT05973448 | The Nightlight Falls Prevention Study | Not applicable | Recruiting | United States |
| NCT06864403 | Mirikizumab in the Treatment of Chronic Inflammatory Conditions of the Pouch | Phase 4 | Recruiting | United States |
| NCT06977178 | Adverse Adolescent Pathways to Substance Use | Not applicable | Recruiting | United States |
| NCT06358885 | IGHID 12230 - An Implementation Trial of an Experiential Brief Alcohol Intervention for HIV Prevention | Not applicable | Active, not recruiting | Vietnam |
| NCT06927037 | Immersive Physical Therapy in the Neonatal Intensive Care Unit (NICU) | Not applicable | Recruiting | United States |
| NCT03554356 | Nitrous Oxide For Endoscopic Ablation of Refractory Barrett's Esophagus (NO FEAR-BE) | Not applicable | Active, not recruiting | United States |
| NCT03838536 | Synergistic Activity of Human Milk Nutrients and Infant Cognition | Not applicable | Recruiting | United States |
| NCT07868536 | Post-traumatic Estradiol Administration and Care Evaluation (PEACE) | Phase 2 | Not yet recruiting | |
| NCT07216820 | Interscalene vs Phrenic-sparing Blocks in Obesity and Effect of Maximum Inspiratory Pressure | Not applicable | Recruiting | United States |
| NCT06228755 | MAGIC Study: More Access to Group Integrative Care | Not applicable | Recruiting | United States |
| NCT07600190 | Anakinra Rescue Treatment for Moderate Asthma Attacks (ARTMA) | Phase 1 | Not yet recruiting | United States |
| NCT07526558 | Mast Cell Treatment in Post-tick Bite Illness (PTBI) | Phase 2 | Not yet recruiting | United States |
| NCT06915428 | Personalized Care for Prenatal Stress Reduction & Prevention of Preterm Birth (PTB) Disparities | Not applicable | Not yet recruiting | United States |
| NCT02738892 | Zambian Preterm Birth Prevention Study | Not applicable | Active, not recruiting | Zambia |
| NCT06587230 | Teachers Leading the Front Lines - North Carolina (Tealeaf-NC) | Not applicable | Recruiting | United States |
| NCT06594913 | Eating Disorders Genetics Initiative 2 | Not applicable | Recruiting | Australia, Mexico, New Zealand, Sweden +1 |
| NCT02427269 | University of North Carolina (UNC) Barrett's Esophagus and Esophageal Cancer Biorepository | Not applicable | Recruiting | United States |
| NCT06744231 | Thriving Hearts: Healing-Centered, Integrated, Community Maternity Care | Not applicable | Recruiting | United States |
| NCT07799480 | Single Session Personalized Aperiodic Transcranial Alternating Current Stimulation (PandA-tACS) for Antenatal… | Not applicable | Not yet recruiting |
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Sources: ClinicalTrials.gov (U.S. National Library of Medicine, public domain) and the EU Clinical Trials Information System public portal (European Medicines Agency), data as of 2026-10-25. A trial that one register cites in the other is shown once. Organisation-level data only: investigators, contact persons and site names are not stored, and a sponsor that could be a private person is withheld. Sponsor-to-website matches are made by name and can be wrong; check the register before relying on a record. Independent of the NLM, NIH and EMA.
Cite as: Arcadium Data, "University of North Carolina, Chapel Hill clinical trials: 164 open, 20 in phase 3", https://arcadiumdata.io/clinical-trials/sponsor/university-of-north-carolina-chapel-hill/, data as of 2026-10-25.