UNC Lineberger Comprehensive Cancer Center: clinical-trial pipeline
UNC Lineberger Comprehensive Cancer Center is the sponsor of 421 clinical trials in ClinicalTrials.gov and the EU CTIS portal; 122 are not yet finished and 7 were first posted in the last 90 days. Source: Arcadium Data, data as of .
Trials by phase
| Phase | Trials |
|---|---|
| Not applicable | 235 |
| Phase 2 | 101 |
| Phase 1 | 54 |
| Early phase 1 | 15 |
| Phase 1/2 | 13 |
| Phase 3 | 2 |
| Phase 4 | 1 |
Trials by status
| Status | Trials |
|---|---|
| Completed | 236 |
| Recruiting | 73 |
| Terminated | 40 |
| Active, not recruiting | 26 |
| Not yet recruiting | 23 |
| Withdrawn or not authorised | 21 |
| Suspended or halted | 2 |
Condition areas
| Area | Trials |
|---|---|
| Oncology | 374 |
| Women's health and obstetrics | 42 |
| Nephrology and urology | 41 |
| Gastroenterology and liver | 23 |
| Infectious disease and vaccines | 21 |
| Immunology and rheumatology | 15 |
| Metabolic and endocrine (diabetes, obesity) | 14 |
| Rare and genetic diseases | 12 |
| Haematology | 10 |
| Musculoskeletal | 7 |
| Psychiatry and mental health | 4 |
| Respiratory | 4 |
Countries
| Country | Trials |
|---|---|
| United States | 390 |
| Malawi | 8 |
| Kenya | 5 |
| South Africa | 4 |
| Ireland | 1 |
| Uganda | 1 |
| Zimbabwe | 1 |
Latest changes
| Day | Change | Trial |
|---|---|---|
| 2026-10-21 | New trial posted | Lucid BE Biomarkers Study |
| 2026-10-09 | New trial posted | Assessing Survival Outcomes With Checkpoint Inhibition ExteNded vs Discontinued in Endome… |
| 2026-10-09 | New trial posted | BLinatumomab and iNKT in Relapsed B-Cell ALL |
| 2026-09-18 | New trial posted | Feasibility Pilot of AYA-PARTNER |
| 2026-09-17 | New trial posted | The STRONG Nutrition Support Study for People With Pancreatic Cancer |
| 2026-09-09 | New trial posted | A Decision Support Tool for Pancreatic Cancer Screening -Aim 2 |
| 2026-08-26 | New trial posted | Keep Social Randomized Controlled Trial for Young Adults With Cancer |
Open trials
The 25 most recently changed open trials.
| Registry id | Title | Phase | Status | Countries |
|---|---|---|---|---|
| NCT05592665 | PRO-VISION: Patient Reported Outcomes-Based Monitoring of VEGF-Inhibitor Side Effects in ONcology | Not applicable | Active, not recruiting | United States |
| NCT07214610 | Integrating Biological, Clinical, and Behavioral Factors to Improve Breast Cancer Outcomes - Carolina Breast… | Not applicable | Recruiting | United States |
| NCT02663297 | Administration of T Lymphocytes for Prevention of Relapse of Lymphomas | Phase 1 | Active, not recruiting | United States |
| NCT06075316 | Improving Thoracic Surgical Care Using Electronic Patient-Reported Outcomes (ePROS) | Not applicable | Recruiting | United States |
| NCT06902376 | XL092 and Cemiplimab in BRAF WT Thyroid Cancer | Phase 1 | Recruiting | United States |
| NCT03174275 | Carboplatin, Nab-Paclitaxel, Durvalumab Before Surgery and Adjuvant Therapy in Head and Neck Squamous Cell Ca… | Phase 2 | Active, not recruiting | United States |
| NCT05440929 | Evaluation of the Acceptability, Appropriateness, and Feasibility/Usability of a Metastatic Breast-cancer Spe… | Not applicable | Recruiting | United States |
| NCT04753086 | Patient Related Outcomes for Gynecologic Radiation Oncology | Not applicable | Active, not recruiting | United States |
| NCT06727773 | Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline Du… | Phase 2 | Recruiting | United States |
| NCT07292818 | Hyaluronic Acid-based Gel Spacers in Gynecologic Malignancies | Phase 1 | Recruiting | United States |
| NCT06702592 | Virtual Testis Cancer Lay Support and Survivorship Aim 2 | Not applicable | Not yet recruiting | United States |
| NCT07605949 | Revumenib, Azacitidine, and VENetoclax in Newly Diagnosed KMT2A-Rearranged AML | Phase 2 | Not yet recruiting | United States |
| NCT03769415 | Harnessing Analysis RNA Expression and Molecular Subtype to Optimize Novel TherapY MBCA | Not applicable | Recruiting | United States |
| NCT07479199 | Local Radiofrequency Ablation Plus External Beam Radiation for the Treatment of Painful Thoracic and Lumbar S… | Not applicable | Recruiting | United States |
| NCT06989489 | Implementation of an Oral Chemotherapy Adherence Intervention | Not applicable | Recruiting | United States |
| NCT07520188 | C-3002: Enhancing Cervical Cancer Screening Access and Follow-up Care at 'CASCADE' Clinical Sites in the Unit… | Not applicable | Not yet recruiting | United States |
| NCT06026098 | Evaluation of Impact of AI Assistance on Workload Associated w Preparation of Rare Tumor Case Repts | Not applicable | Not yet recruiting | United States |
| NCT05656807 | Evaluation of Child Care Staff Weight Management Program | Not applicable | Active, not recruiting | United States |
| NCT05096923 | UNC Childhood, Adolescent, and Young Adult Cancer Cohort | Not applicable | Recruiting | United States |
| NCT06073067 | GRID Therapy for Extremity Soft Tissue Sarcoma | Not applicable | Recruiting | United States |
| NCT04073966 | MRI Biomarkers for Radiation-Induced Neurocognitive Decline Following SRS of Newly Diagnosed Brain Mets | Not applicable | Recruiting | United States |
| NCT03016377 | Administration of Autologous CAR-T CD19 Antigen With Inducible Safety Switch in Patients With Relapsed/Refrac… | Phase 1 | Active, not recruiting | United States |
| NCT03454035 | Ulixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid Tumors | Phase 1 | Recruiting | United States |
| NCT05742386 | Impact of Standing Orders Optimization | Not applicable | Active, not recruiting | United States |
| NCT07078838 | Tirzepatide in Women With Obesity and Endometrial Intra-epithelial Neoplasia or Grade 1 Endometrial Cancer | Phase 2 | Not yet recruiting | United States |
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Sources: ClinicalTrials.gov (U.S. National Library of Medicine, public domain) and the EU Clinical Trials Information System public portal (European Medicines Agency), data as of 2026-10-25. A trial that one register cites in the other is shown once. Organisation-level data only: investigators, contact persons and site names are not stored, and a sponsor that could be a private person is withheld. Sponsor-to-website matches are made by name and can be wrong; check the register before relying on a record. Independent of the NLM, NIH and EMA.
Cite as: Arcadium Data, "UNC Lineberger Comprehensive Cancer Center clinical trials: 122 open, 2 in phase 3", https://arcadiumdata.io/clinical-trials/sponsor/unc-lineberger-comprehensive-cancer-center/, data as of 2026-10-25.