The Methodist Hospital Research Institute: clinical-trial pipeline
The Methodist Hospital Research Institute is the sponsor of 160 clinical trials in ClinicalTrials.gov and the EU CTIS portal; 70 are not yet finished and 7 were first posted in the last 90 days. Source: Arcadium Data, data as of .
Trials by phase
| Phase | Trials |
|---|---|
| Not applicable | 69 |
| Phase 2 | 40 |
| Phase 1 | 18 |
| Phase 1/2 | 16 |
| Phase 4 | 13 |
| Phase 2/3 | 2 |
| Phase 3 | 2 |
Trials by status
| Status | Trials |
|---|---|
| Completed | 56 |
| Recruiting | 50 |
| Terminated | 16 |
| Unknown | 14 |
| Active, not recruiting | 13 |
| Not yet recruiting | 7 |
| Withdrawn or not authorised | 4 |
Condition areas
| Area | Trials |
|---|---|
| Oncology | 59 |
| Nephrology and urology | 49 |
| Neurology | 21 |
| Immunology and rheumatology | 13 |
| Infectious disease and vaccines | 12 |
| Cardiovascular | 10 |
| Musculoskeletal | 8 |
| Gastroenterology and liver | 6 |
| Respiratory | 4 |
| Metabolic and endocrine (diabetes, obesity) | 3 |
| Rare and genetic diseases | 3 |
| Women's health and obstetrics | 2 |
Countries
| Country | Trials |
|---|---|
| United States | 150 |
| Canada | 2 |
| Brazil | 1 |
Latest changes
| Day | Change | Trial |
|---|---|---|
| 2026-09-15 | New trial posted | Semaglutide, Weight Loss, and LNG-IUD for Conservative Treatment of Endometrial Atypical… |
| 2026-09-01 | New trial posted | Use of Apple Vision Pro as Virtual Monitor for Diagnostic and Therapeutic Procedures |
| 2026-09-01 | New trial posted | Neoadjuvant Intraprostatic OnabotulinumtoxinA Before Radical Prostatectomy for High-Risk… |
| 2026-08-31 | New trial posted | Transforming Curiosity Into Donation |
| 2026-08-31 | New trial posted | Strategies to Transform Kidney Care and Improve Pursuit of Transplant |
| 2026-08-31 | New trial posted | Modifiable Factors Affecting Racial Disparities in Kidney Donation |
| 2026-08-31 | New trial posted | Nasal Dilator Therapy for Patulous Eustachian Tube Dysfunction |
Open trials
The 25 most recently changed open trials.
| Registry id | Title | Phase | Status | Countries |
|---|---|---|---|---|
| NCT06384651 | Intraosseous vs. Intravenous Vancomycin Administration in Total Ankle Arthroplasty | Phase 4 | Recruiting | United States |
| NCT06664827 | Blood Flow Restriction (BFR) Training on the Ulnar Collateral Ligament (UCL) | Not applicable | Recruiting | United States |
| NCT05305924 | Fulvestrant+Abemaciclib With Run-In of Fulvestrant in Er-Positive, Her2-Negative Metastatic Breast Cancer | Phase 2 | Recruiting | United States |
| NCT05831774 | IO Vancomycin in TSA | Phase 4 | Active, not recruiting | United States |
| NCT06930690 | Dexamethasone for Ureteral STent Symptoms (DUSTS) | Phase 1/2 | Recruiting | United States |
| NCT07283068 | IO Vancomycin Into the Medial Malleolus vs IV Administration in Revision TKA | Not applicable | Not yet recruiting | |
| NCT07042685 | Trial of 5-Fluorouracil (5FU)-Based Therapy in Combination With Fruquintinib in Patients With Locally Advance… | Phase 2 | Recruiting | United States |
| NCT03603405 | HSV-tk and XRT and Chemotherapy for Newly Diagnosed GBM | Phase 1/2 | Recruiting | United States |
| NCT05511246 | Venous Ethanol for Ventricular Tachycardia | Phase 2 | Recruiting | United States |
| NCT07383649 | Trial to Study Anti- HCMV Therapy in Breast Cancer Patients With Progressive Intracranial Metastases and CMV… | Phase 2 | Recruiting | United States |
| NCT05185505 | Atezolizumab and Bevacizumab Pre-Liver Transplantation for Patients With Hepatocellular Carcinoma Beyond Mila… | Phase 4 | Recruiting | Canada, United States |
| NCT06798623 | Anterior Cruciate Ligament (ACL) Reconstruction With Autologous Fat Pad Derived Mesenchymal Stem Cells | Phase 1 | Recruiting | United States |
| NCT06286800 | Personalized Transcranial Direct Current Stimulation in Stroke Recovery | Not applicable | Recruiting | United States |
| NCT06887218 | 5-Fluorouracil/Leucovorin (5FU/LV) in Combination With Regorafenib in Patients With Metastatic Colorectal Can… | Phase 2 | Recruiting | United States |
| NCT06666608 | Bone Stimulator for Spondylolysis | Not applicable | Recruiting | United States |
| NCT06640491 | Intraosseous (IO) Cefazolin and Vancomycin in Primary Total Knee Arthroplasty (TKA) | Phase 1/2 | Recruiting | United States |
| NCT03820141 | Durvalumab With Trastuzumab and Pertuzumab in HER2-Enriched Breast Cancer | Phase 2 | Active, not recruiting | United States |
| NCT06748144 | IO Vancomycin Spine | Phase 2/3 | Not yet recruiting | United States |
| NCT06213012 | Harnessing Neuroplasticity of Postural Sensorimotor Networks Using Non-Invasive Spinal Neuromodulation to Max… | Not applicable | Recruiting | United States |
| NCT03971487 | Ocrelizumab for Psychosis by Autoimmunity | Phase 1/2 | Recruiting | United States |
| NCT06072703 | Neuromodulating Cortical Regions Involved in Neurogenic Bladder in MS | Not applicable | Recruiting | United States |
| NCT07218484 | VoiceLove Digital Therapy for Delirium in the ICU | Not applicable | Recruiting | United States |
| NCT05241340 | Neoadjuvant Sasanlimab With Radiation as an in Situ Vaccine for Cisplatin-ineligible Muscle Invasive Bladder… | Phase 2 | Active, not recruiting | United States |
| NCT03742245 | Olaparib in Combination With Vorinostat in Patients With Relapsed/Refractory and/or Metastatic Breast Cancer | Phase 1 | Active, not recruiting | United States |
| NCT04494724 | Clazakizumab vs. Placebo - COVID-19 Infection | Phase 2 | Recruiting | United States |
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Sources: ClinicalTrials.gov (U.S. National Library of Medicine, public domain) and the EU Clinical Trials Information System public portal (European Medicines Agency), data as of 2026-10-25. A trial that one register cites in the other is shown once. Organisation-level data only: investigators, contact persons and site names are not stored, and a sponsor that could be a private person is withheld. Sponsor-to-website matches are made by name and can be wrong; check the register before relying on a record. Independent of the NLM, NIH and EMA.
Cite as: Arcadium Data, "The Methodist Hospital Research Institute clinical trials: 70 open, 4 in phase 3", https://arcadiumdata.io/clinical-trials/sponsor/the-methodist-hospital-research-institute/, data as of 2026-10-25.