The Cleveland Clinic: clinical-trial pipeline
The Cleveland Clinic is the sponsor of 830 clinical trials in ClinicalTrials.gov and the EU CTIS portal; 161 are not yet finished and 9 were first posted in the last 90 days. Source: Arcadium Data, data as of .
Trials by phase
| Phase | Trials |
|---|---|
| Not applicable | 631 |
| Phase 4 | 68 |
| Phase 2 | 46 |
| Phase 3 | 26 |
| Phase 1 | 23 |
| Early phase 1 | 20 |
| Phase 1/2 | 9 |
| Phase 2/3 | 5 |
| Not stated | 2 |
Trials by status
| Status | Trials |
|---|---|
| Completed | 491 |
| Terminated | 110 |
| Recruiting | 105 |
| Withdrawn or not authorised | 60 |
| Active, not recruiting | 42 |
| Not yet recruiting | 14 |
| Unknown | 7 |
| Suspended or halted | 1 |
Condition areas
| Area | Trials |
|---|---|
| Cardiovascular | 160 |
| Neurology | 70 |
| Metabolic and endocrine (diabetes, obesity) | 67 |
| Oncology | 65 |
| Nephrology and urology | 64 |
| Gastroenterology and liver | 61 |
| Musculoskeletal | 52 |
| Immunology and rheumatology | 49 |
| Infectious disease and vaccines | 43 |
| Rare and genetic diseases | 42 |
| Respiratory | 29 |
| Psychiatry and mental health | 26 |
Countries
| Country | Trials |
|---|---|
| United States | 759 |
| Austria | 8 |
| China | 8 |
| El Salvador | 6 |
| Canada | 5 |
| Germany | 4 |
| United Kingdom | 3 |
| Ireland | 3 |
| India | 3 |
| Italy | 3 |
| Argentina | 2 |
| Switzerland | 2 |
| Spain | 2 |
| Japan | 2 |
| Belgium | 1 |
Latest changes
| Day | Change | Trial |
|---|---|---|
| 2026-10-23 | New trial posted | SGB for Prevention of Postop A-Fib After Cardiac SurgeryTrial |
| 2026-10-20 | New trial posted | Utilization of Aerobic Exercise to Maintain Neurologic Health |
| 2026-10-15 | New trial posted | An AI-powered Virtual Reality Brief Intervention for Hospitalized Patients With Alcohol-A… |
| 2026-09-29 | New trial posted | Choose Myself (Before) Losing Myself |
| 2026-09-17 | New trial posted | Exercise Training Decreases Alcohol Consumption and Tissue Injury by an FGF21-dependent M… |
| 2026-09-10 | New trial posted | NIRAF-camera Versus Conventional Surgery in Preoperative Imaging Negative Primary Hyperpa… |
| 2026-09-10 | New trial posted | Robotic Adrenalectomy With Versus Without Indocyanine Green Fluorescence Imaging |
| 2026-09-08 | New trial posted | Evaluation of 4D Intracardiac Echocardiography (ICE) During Structural Heart and Electrop… |
| 2026-08-28 | New trial posted | Effects of Non-invasive Brain Stimulation on Pain Avoidance Behavior in Chronic Pain Pati… |
Open trials
The 25 most recently changed open trials.
| Registry id | Title | Phase | Status | Countries |
|---|---|---|---|---|
| NCT07222072 | Methadone to Reduce Chronic Opioid Use After Major Spine Surgery: The MEND Pilot Feasibility Study | Phase 4 | Recruiting | United States |
| NCT07442747 | Neural Mechanisms of Aerobic Exercise Benefits in PD With DBS | Phase 2 | Recruiting | United States |
| NCT04978636 | Low Tidal Volume Ventilation With Hyperoxia Avoidance During Cardiopulmonary Bypass (The FOCUS Trial) | Not applicable | Active, not recruiting | United States |
| NCT07568275 | Comparison of Angiotensin II to Standard Dose Vasopressors on Change in Arterial Elastance | Early phase 1 | Active, not recruiting | United States |
| NCT04660955 | MOON Onsite MRI 10 Years After ACL Reconstruction | Not applicable | Recruiting | United States |
| NCT03030755 | Corneal Elastography and Patient Specific Modeling | Not applicable | Recruiting | United States |
| NCT07695454 | Imaging in Semaglutide Study | Not applicable | Recruiting | United States |
| NCT05086978 | Novel Clinical Utility of Retinal Imaging in Patients With Heart Failure | Not applicable | Recruiting | United States |
| NCT03224949 | Comparison of ALD, NASH, and Healthy Control Patients | Not applicable | Recruiting | United States |
| NCT03113929 | Quantitative MRI for Non-invasive Assessment of Severity of Alcoholic Liver Disease (ALD) | Not applicable | Active, not recruiting | United States |
| NCT07574437 | At-Home Bowel Stimulation | Not applicable | Recruiting | United States |
| NCT07893275 | SGB for Prevention of Postop A-Fib After Cardiac SurgeryTrial | Phase 3 | Not yet recruiting | |
| NCT02716441 | Rotator Cuff Failure With Continuity | Not applicable | Active, not recruiting | United States |
| NCT07087587 | Sleep Apnea Triggers of Atrial Fibrillation: N-of-1 Randomized Control Trial (SPARTA): | Not applicable | Recruiting | United States |
| NCT07701655 | Personalized Approach to Celiac Disease Diagnosis | Not applicable | Not yet recruiting | |
| NCT04513808 | Total Intravenous Anesthesia and Recurrence Free Survival | Phase 3 | Recruiting | China |
| NCT01536522 | Asthma Inflammation Research | Early phase 1 | Recruiting | United States |
| NCT05628948 | Vascular Lab Resource (VLR) Biorepository | Not applicable | Recruiting | United States |
| NCT05598879 | Global Cardio Oncology Registry | Not applicable | Recruiting | United States |
| NCT06179654 | Preoperative Pelvic Floor Physical Therapy to Minimize Stress Urinary Incontinence After Holmium Laser Enucle… | Not applicable | Active, not recruiting | United States |
| NCT03023696 | Can Prophylactic Foraminotomy Prevent C5 Palsy | Not applicable | Recruiting | United States |
| NCT05911165 | Impact of Surgical Coaching on Resident ObGyn Laparoscopic Skills | Not applicable | Active, not recruiting | United States |
| NCT03535298 | Determining the Effectiveness of earLy Intensive Versus Escalation Approaches for RRMS | Phase 4 | Active, not recruiting | United Kingdom, United States |
| NCT07874802 | An AI-powered Virtual Reality Brief Intervention for Hospitalized Patients With Alcohol-Associated Liver Dise… | Phase 1 | Not yet recruiting | |
| NCT04191681 | Safety and Efficacy of ARNI After LVAD ImplanT (SEAL-IT) Study | Phase 4 | Recruiting | United States |
Hiring for clinical development
The Cleveland Clinic has 2 open jobs with a clinical, regulatory, safety, biostatistics or medical-affairs title on its own career sites: hiring profile of ccf.org.
Website: ccf.org. All sponsors: clinical-trial pipeline by sponsor.
Track a sponsor's pipeline
The API returns the same trials by sponsor website, phase, status, condition and country with a change feed, joined to hiring and public contract awards. Try it without a key on one sponsor.
Sources: ClinicalTrials.gov (U.S. National Library of Medicine, public domain) and the EU Clinical Trials Information System public portal (European Medicines Agency), data as of 2026-10-25. A trial that one register cites in the other is shown once. Organisation-level data only: investigators, contact persons and site names are not stored, and a sponsor that could be a private person is withheld. Sponsor-to-website matches are made by name and can be wrong; check the register before relying on a record. Independent of the NLM, NIH and EMA.
Cite as: Arcadium Data, "The Cleveland Clinic clinical trials: 161 open, 31 in phase 3", https://arcadiumdata.io/clinical-trials/sponsor/ccf-org/, data as of 2026-10-25.