Amsterdam UMC, location VUmc: clinical-trial pipeline

Amsterdam UMC, location VUmc is the sponsor of 304 clinical trials in ClinicalTrials.gov and the EU CTIS portal; 71 are not yet finished and 4 were first posted in the last 90 days. Source: Arcadium Data, data as of .

Open trials71
Phase 2/3 and 318
Countries25
New in 90 days4

Trials by phase

PhaseTrials
Not applicable207
Phase 436
Phase 219
Phase 113
Phase 312
Phase 1/29
Phase 2/36
Early phase 12

Trials by status

StatusTrials
Completed129
Unknown82
Recruiting44
Terminated19
Not yet recruiting17
Active, not recruiting10
Withdrawn or not authorised2
Suspended or halted1

Condition areas

AreaTrials
Oncology94
Cardiovascular51
Neurology30
Metabolic and endocrine (diabetes, obesity)29
Nephrology and urology23
Gastroenterology and liver22
Psychiatry and mental health16
Respiratory15
Infectious disease and vaccines11
Rare and genetic diseases9
Musculoskeletal8
Ophthalmology6

Countries

CountryTrials
Netherlands279
Germany9
United Kingdom7
Denmark6
Spain4
Finland4
France4
Norway3
Belgium2
Italy2
Poland2
Portugal2
Sweden2
Australia1
Canada1

Latest changes

DayChangeTrial
2026-10-07New trial postedALSO-PERFORM Study. ALternating Stereotaxic Or PElvic Radiotherapy FOR Metachronic Metast…
2026-09-29New trial postedEndoscopic (EID) Versus Surgical (TAMIS) Local Excision for Early Stage Rectal Cancer
2026-09-01New trial postedIntegration of Whole-Genome Sequencing PrOfiles and ImmuNe StATus in Cancer
2026-08-28New trial postedBack on Track: Evaluation of an Occupational Reintegration Protocol for Employees With Mu…

Open trials

The 25 most recently changed open trials.

Registry idTitlePhaseStatusCountries
NCT06384560Neoadjuvant Triple Therapy for (Borderline) Resectable Pancreatic Cancer (PREOPANC-5)Phase 1/2RecruitingNetherlands
NCT06457789Assessment of PET Tracers to Evaluate T Cell Change and Activation in Relation to Immunotherapy Treatment Res…Not applicableRecruitingNetherlands
NCT04225312Personalized Extended Interval Dosing of Natalizumab in Relapsing Remitting Multiple SclerosisPhase 4Active, not recruitingNetherlands
NCT06687876Metformin as a Metabolic Intervention in Oesophageal Adenocarcinomas to Improve Response to Neoadjuvant Chemo…Phase 2RecruitingNetherlands
NCT05957250[68Ga]Ga-FAPI-46 Positron Emission Tomography (PET) Scan to Improve the Imaging of Pancreatic and Bile Duct C…Not applicableRecruitingNetherlands
NCT04392037Iberdomide Combined With Low-dose Cyclophosphamide and DexamethasonePhase 2Active, not recruitingNetherlands
NCT05861505COLLISION RELAPSE TrialPhase 3RecruitingNetherlands
NCT02371304Rectal Preserving Treatment for Early Rectal Cancer. A Multi-centred Randomised Trial of Radical Surgery Vers…Phase 3RecruitingFrance, Netherlands
NCT04307953Saracatinib Trial TO Prevent FOPPhase 2Active, not recruitingGermany, United Kingdom, Netherlands
NCT06658522Right Ventricular Compensation With Sotatercept: A Prospective Single Arm Open Label Phase 4 Study to Evaluat…Phase 4Not yet recruitingNetherlands
NCT07781722Tacrolimus as Prophylaxis of Post-ERCP PancreatitisPhase 4RecruitingNetherlands
NCT07615881Comparing Intravenous or Intradermal Administration of Anti-CTLA-4 in Combination With Anti-PD1 Treatment in…Phase 1/2Not yet recruiting
NCT05834855Non-inferiority Study of Rituximab Compared to Ocrelizumab in Relapsing MSPhase 3RecruitingNetherlands
NCT06623565Extensive Resection of Malignant Brain Tumors Using Advanced Imaging TechniquesNot applicableRecruitingNetherlands
NCT05088785Dynamic and Test-retest Whole Body [18F]FES PET Imaging in Patients With Metastatic ER+ Breast CancerNot applicableActive, not recruitingNetherlands
NCT06824961Does Increasing the Compression Pause From 3 to 5 Seconds in Mechanical Compression Devices Increase Ventilat…Not applicableRecruitingNetherlands
NCT07278206Brain Stimulation in Long COVIDNot applicableRecruitingNetherlands
NCT06282562FeelFit: High-intensity Interval Training to Improve Self-reported Physical Fitness in Brain Tumor PatientsNot applicableRecruitingNetherlands
NCT07863336ALSO-PERFORM Study. ALternating Stereotaxic Or PElvic Radiotherapy FOR Metachronic Metastatic Prostate CancerNot applicableNot yet recruiting
NCT06298695Schema Therapy for Treatment-resistant Anxiety DisordersNot applicableNot yet recruiting
NCT07155681Evaluating Healthcare Professionals' Satisfaction and Stress Mitigation Using Virtual Reality Intervention in…Not applicableNot yet recruitingGermany, Denmark
NCT04815928Registry of Patients That Have Undergone ICA or PCINot applicableRecruitingNetherlands
NCT06185556COLDFIRE-III Trial: Efficacy of Irreversible Electroporation and Stereotactic Body Radiotherapy for Perivascu…Phase 2/3RecruitingNetherlands
NCT05296161B Cell Tailored Ocrelizumab Versus Standard Ocrelizumab in Relapsing Remitting Multiple SclerosisPhase 4Active, not recruitingNetherlands
NCT06731361Improved Prescribing for Older Nursing Home PatientsNot applicableRecruitingNetherlands

All sponsors: clinical-trial pipeline by sponsor.

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Sources: ClinicalTrials.gov (U.S. National Library of Medicine, public domain) and the EU Clinical Trials Information System public portal (European Medicines Agency), data as of 2026-10-25. A trial that one register cites in the other is shown once. Organisation-level data only: investigators, contact persons and site names are not stored, and a sponsor that could be a private person is withheld. Sponsor-to-website matches are made by name and can be wrong; check the register before relying on a record. Independent of the NLM, NIH and EMA.

Cite as: Arcadium Data, "Amsterdam UMC, location VUmc clinical trials: 71 open, 18 in phase 3", https://arcadiumdata.io/clinical-trials/sponsor/amsterdam-umc-location-vumc/, data as of 2026-10-25.